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Guest Sean Hashmi, MD The Permanente Federation Podcast transcript Transcript is autogenerated
Atherosclerosis 237 , 562567 (2014)
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Rushing creates foam, and foam means denatured peptide
Chronic Complication Mechanisms: Sustained hyperglycemia damages small vessels (microvascular disease) via multiple mechanisms including AGE accumulation, protein kinase C activation, and hexosamine pathway flux
Indeed GLP-1R agonists proved to be efficient for the treatment of type 2 diabetes mellitus 37 and studies indicate they could be used in other indications 26,43,44 such as obesity 45,46 , adverse cardiovascular events 25 , cognitive disorders 44 and non-alcoholic steatohepatitis (NASH) 47
