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PQQ is so effective because it is very efficient at transferring electrons

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The ratio of reduced glutathione to oxidized glutathione is often a measure of health, as having high amounts of oxidized glutathione is present in times of extreme stress or injury, shock, and in neurodegenerative diseases

87 A related principle may also operate in inflammatory tissue niches, where oxidized lipids, often associated with lipoprotein particles such as low-density lipoprotein (LDL), are cleared by resident immune cells, thereby modulating local ferroptotic thresholds and potentially influencing the permissiveness of propagation