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injection of 50 mg/kg sodium pentobarbital (Sigma), and thoracic aorta was carefully dissected and maintained at 37 C in Krebs solution containing 118.2 mM NaCl, 4.7 mM KCl, 1.2 mM MgSO 4 , 25 mM NaHCO 3 , 1.2 mM KH 2 PO 4 , 1.9 mM CaCl 2 and 11.7 mM dextrose (pH 7.4, 95% O 2 , 5% CO 2 )

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Thymosin beta-4 is a low-molecular-weight protein with a well-documented role in tissue repair processes, including wound healing, angiogenesis and peptide signaling, cellular proliferation and migration, re-epithelialization, and modulation of inflammatory responses

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Compared with the placebo group, treatment with the GLP-1 analog liraglutide reduced the rates of non-fatal myocardial infarction, non-fatal stroke and hospitalization for heart failure (52)

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