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Tirzepatide is the agonist of GLP-1 receptor and glucose-dependent insulinotropic polypeptide (GIP) receptor, which can reduce body weight and improve cardiac metabolism by subcutaneous injection once a week (Jastreboff et al 2022)
The age-related decline in vagal tone and cardiometabolic impairment further limits efficacy
She is an advocate for natural treatment, including homeopathy, which she chose, together with traditional medicine, when she had cancer years ago
In June 2025, the European Medicines Agency officially recognized NAION as a very rare side effect of semaglutide after reviewing all data, concluding it may affect up to 1 in 10,000 people and recommending product information updates
People least likely to quit using GLP-1 drugs are those using them to manage diabetes and those with higher incomes
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