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From these studies, we observed that only approximately 50% of the semaglutide was retained in these hydrogels, while nearly 100% of the liraglutide was retained over prolonged timeframes in this release format where hydrogel erosion is negligible over time (Figure 3D

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Even though NO is physiologically critical to vasodilation and neurotransmission (251), excess NO and RNS are damaging as they directly attack antioxidant enzymes such as catalase (298), promoting redox imbalance