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To date, several randomized clinical trials (RCTs) have investigated the potential benefits of methylene blue administration in the treatment of Alzheimers disease

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doi:10.1016/j.cmet.2018.02.011 High-Dose Vitamin C IV: Collagen Synthesis and Photoprotection Intravenous vitamin C at 10-25g achieves plasma concentrations of 13,000-20,000 umol/L 70-100x higher than maximum oral absorption of 220 umol/L

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Some researchers suggest metabolic shifts as the body adjusts to altered fat metabolism could trigger them