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[] Accelerated detoxification N-acetylcysteine (NAC) is the main antidote for paracetamol overdose, acting by restoring glutathione levels, [] Figure 3 illustrates the mechanism of paracetamols action, showing its metabolic pathways, including the production of NAPQI and its detoxification by glutathione

Aroda VR, Edelstein SL, Goldberg RB, Knowler WC, Marcovina SM, Orchard TJ, Bray GA, Schade DS, Temprosa MG, White NH, Crandall JP

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