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NICE guidance on obesity management (CG189) emphasises evidence-based interventions including dietary modification, increased physical activity, behavioural therapy, andwhere appropriatepharmacotherapy with licensed medications such as orlistat or semaglutide (NICE TA875)

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We dont know about possible interactions with medications or long-term risks

Can J Physiol Pharmacol 89 , 497504, (2011)

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