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doi:10.1016/0003-2697(88)90564-7

By addressing insulin resistance, promoting weight loss, and improving ovulatory function, these medications can enhance reproductive health and increase the chances of conception in women with PCOS

Many long-term spinal CSF leak patients vacillate between high and low pressure, and anecdotally some are finding support with these medications at microdoses to help regulate their CSF dynamics

Studies indicate particular affinity for select signaling cascades under controlled conditions

The medication also has mild antidepressant effects, which can benefit people dealing with both mood issues and weight management simultaneously

PMID: 11382369