Rarely, someone may experience mild side effects such as nausea, headache, or digestive upset
Functions as a for metabolic reaction required for synthesis of purines and pyrimidines: co-enzyme The reaction depends on methyl cobalamin as a co-factor and is also dependent on folate, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to form methionine and tetrahydrofolate
Understanding these contraindications is essential for healthcare providers and patients to ensure safe and appropriate use of this compounded medication
These include: Metformin use : Metformin impairs vitamin B12 absorption in the intestine
In fact, a 2008 study found that after taking a 1,000 mcg oral supplement, only approximately 1.3% (or 13 mcg) of B12 was absorbed into the bloodstream
Symptoms requiring immediate medical attention include difficulty breathing, facial swelling, or widespread urticaria