Common reconstitution volumes: 20mg vial + 2mL BAC water = 10mg/mL concentration 40mg vial + 2mL BAC water = 20mg/mL concentration 40mg vial + 3mL BAC water = 13mg/mL concentration Add diluent slowly: Insert the needle into the vial at an angle and allow the water to flow down the inside wall of the vial
Injections are usually prescribed for a diagnosed deficiency, sometimes for life, as in pernicious anemia or after stomach surgery
Doses in preclinical studies have typically ranged from 10 nanograms to 10 micrograms per kilogram of body weight, administered daily
The arginate salt form is a newer formulation designed for greater stability, particularly in liquid form and in the harsh environment of the GI tract
But as you can see, these high supplement doses may be aggravating (skin-wise) for the average person who receives B12 from dietary sources, such as red meat, chicken, eggs and fish
They govern hormone release, immune activity, cellular repair, appetite regulation, and dozens of other physiological processes