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Address correspondence to: Kalipada Pahan, Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison Street, Suite 310, Chicago, Illinois 60612, USA

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Preliminary work with previously sedentary subjects failed to indicate performance effects related to VO2max assessed via graded exercise treadmill testing or anaerobic energy assessed via a 30-second cycle sprint

One study found that the combined intake of both preparations over a period of two months was able to reduce lactate levels and headaches