The optical density (OD) values for the standards of all immunoassays tested were within the range established by the manufacturers, except for the last point of the standard curve (the most concentrated), which was higher than the declared in the human free BDNF Quantikine ELISA (#DBD00, R&D Systems), the high sensitivity pro-BDNF human ELISA kit (#SK00752-09, Aviscera Bioscience), the human pro-BDNF ELISA (#EH4255, FineTest) and the human BDNF ELISA kit (#EH0043, FineTest) (Supplementary Figures S2, S3 and S4)
The data were presented at the European Association for the Study of Diabetes (EASD) congress 2025 in Vienna, Austria
Freezing is excellent for long-term storage (months), but it's terrible if you need to access the peptide frequently
AUTO PURGE (OPTIONAL) The pneumatic valve is operated by a preset controller to purge the conical tank throughout the day
Researchers must follow institutional protocols and regulatory guidelines and ensure all peptide compound use is for research only
Current senolytic agents are primarily employed in cancer therapies, such as doxorubicin, trametinib, and cell cycle-targeting drugs like palbociclib (Tao et al., 2016)