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Another emerging treatment, CagriSema , has shown about 23% weight loss in 68 weeks [8]
What constitutes unresponsive: Clinically, per manufacture, a patient should not be considered as unresponsive to therapy until less than 5% weight loss over the course of 3 months of GLP1/GIP medication at prescribed dose has been established
Some participants in both trials achieved over 30% weight loss, while others responded minimally despite consistent treatment
Published Phase 2 data (Jastreboff et al., New England Journal of Medicine , 2023) demonstrated substantial reductions in body weight and improvements in cardiometabolic markers
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