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Serious but rare risks include pancreatitis, gallbladder disease, acute kidney injury (usually in the context of severe dehydration from gastrointestinal side effects), and hypersensitivity reactions including anaphylaxis and angioedema
Skou LD, Johansen SK, Okarmus J et al (2024) Pathogenesis of DJ-1/PARK7-mediated Parkinsons disease
Others are engineered to cross the blood-brain barrier and directly engage GLP-1 receptors in the brain, amplifying appetite-suppressing effects
This overgrowth can trigger immune reactions, increase inflammation, and further weaken the skin barrier
Some risks of compounded semaglutide include dosing errors (which can lead to serious side effects), contamination, and illegal sales of counterfeit products, which could be harmful
Gen Comp Endocrinol (2010) 165:6071
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