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Heading the list were the long-awaited results of TECOS, which looked at the cardiovascular (CV) safety of Merck & Co's DPP-4 inhibitor Januvia (sitagliptin) and concluded that there was no elevated risk with the drug in patients with established CV disease

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Key tips for clinicians include: Ask about gallbladder history before starting therapy Monitor for right upper quadrant pain or nausea after meals Educate patients on when to seek medical evaluation For most, the benefits of GLP1 therapy outweigh the risks, but patient awareness is critical for timely diagnosis and care