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Yes, in general, you can take milk thistle with magnesium or zinc supplements

Chapter Six - Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases

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Sufficient essential fatty acid and micronutrient intake promote prostaglandin balance and vascular health in the endometrium

You have some wiggle room, but if you fall off your schedule for too long, those signs of fatigue will inevitably return, and they almost always arrive on the scene before any other symptom does