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CHIP was repeatedly found to be associated with a variety of adverse health outcomes, including hematological cancers, and also with a significantly elevated risk of atherosclerotic cardiovascular disorders which are a leading cause of death in the elderly (Evans et al., 2020

Chronic stress, poor diet, and exposure to toxins like pollution, alcohol, smoking, and processed foods strain the bodys defenses

Prolonged overdose of B6 (150-200 mg/day) over weeks can cause severe sensory-nervous-system dysfunction and ataxia.37 With normal usage serious adverse effects are not reported for pyridoxine (vitamin B6), however, diarrhoea, emesis and rosacea-like dermatitis may be observed in some cases (38)

KPV has genuine but narrow evidence: it reduced colitis severity in mice through a PepT1-transporter, NF-Binhibiting mechanism, confirmed by more than one group

doi: 10.1038/s42003-022-03189-z 211 OuwendijkW

Always verify calculations independently before use in any research protocol