SURMOUNT-4 provided the strongest evidence for continued treatment
Most side effects are dose-dependent
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2007;22:E13
This is because the nutrients and powerful antioxidants are delivered directly to your bloodstream, allowing them to be absorbed more quickly and efficiently than if they were taken orally
For example, SGLT2i use leads to a 33% reduction (95% CI 26, 38) in hospitalisation for heart failure (HF) and a 35% reduction (95% CI 19, 47) in the incidence of end-stage kidney disease (ESKD) [3, 4], and GLP-1 RA use leads to a 10% reduction (95% CI 2, 17) in myocardial infarction (MI) and a 17% reduction (95% CI 8, 24) reduction in stroke [2]