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A few extra beats at rest is physiologically insignificant for healthy hearts
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While GLP-1 therapies can result in substantial weight loss with continuous use, an estimated 60% to 70% of patients taking these agents discontinue therapy within the first year
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That means any retatrutide safety profile discussion should separate published Phase 2 adverse event data from emerging Phase 3 safety updates and avoid treating preliminary conference or registry updates as final prescribing-level evidence
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