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Clarkson interjected, Which is not good for girls with curves later on. After Jenna remarked that she and Barbara were chubby as children, Barbara agreed: Well, there was a stage." Clarkson then gave Jenna a high-five, joking, Ive had many stages.
Statistical analyses The trial planned to screen 615 people and randomise 410 participants at 80 study sites in multiple countries
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Although a prior cohort study did not show a statistically significant reduction in major cardiovascular events among patients with no previous history of cardiovascular disease [148], a meta-analysis of eight clinical trials evaluating the effect of GLP-1R agonists on cardiovascular outcomes reported a 14% reduction in major adverse cardiovascular events, with no significant heterogeneity across GLP-1R agonists or subgroups, including patients with or without previous cardiovascular disease [149]
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