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The lack of large, randomized controlled trials makes it unlikely for SUD to become an on-label use anytime soon
Casazza, M
J Clin Invest 135 (2025)
Researchers noted that these adverse effects were mostly mild to moderate in severity and tended to decrease over time as treatment continued
Clayman, senior author of the paper, noted that in a practice seeing more thyroid cancer than almost anywhere globally, they are not seeing a surge of medullary thyroid cancer linked to these medications
GLP-1 receptor agonists like semaglutide and liraglutide, and dual GIP/GLP-1 receptor agonists like tirzepatide, slow gastric emptying, reduce appetite, and improve insulin sensitivity
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