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Gradual discontinuation may reduce rebound effects compared to abrupt cessation

Thorax 57(10):875879 Hamid Q, Tulic MK, Liu MC, Moqbel R (2003) Inflammatory cells in asthma: mechanisms and implications for therapy

This ensures that phytochemicals, such as curcumin, remain intact during circulation/BBB transit but unleash at disease sites (acidic/inflamed brain regions), amplifying Nrf2/antioxidant effects in AD/PD models with minimal off-target toxicity

The cohorts mean BMI was 33.3 kg/m2, and 71.5% of patients met the criterion for obesity (30)

Must be reconstituted with bacteriostatic water before use