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Hyperoxia decreases glycolytic capacity, glycolytic reserve and oxidative phosphorylation in MLE-12 cells and inhibits complex I and II function, but not complex IV in isolated mouse lung mitochondria

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Biochem Biophys Res Commun, 2011

This sensation typically peaks between days 3 and 7 after starting or increasing your dose, then begins to decline noticeably by week 2