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Similar to other metabolic diseases, connected devices can gather objective, continuous data in real-world environments and support clinic-based functional assessments for patients participating in weight-loss trials
As with any significant weight loss, adaptive thermogenesis (a decrease in resting energy expenditure) typically occurs, which may partially offset any metabolic changes
The fat loss is frequently still happening it's just masked by fluid fluctuations
Aging-associated destruction of joints and cartilage degradation in osteoarthritis is correlated with changes in extracellular matrix of articular cartilage, such as cartilage ECM stiffness, and in the levels and solubility profiles of matrix crosslinks, especially pentosidine, as well as reduced thickness of cartilage, proteolysis, advanced glycation and calcification (Eyre et al., 1988
But the real problem was storage
Decreased appetite (and yes, this is a good thing!) One of the main ways Mounjaro works is by curbing hunger, so feeling less hungry or less likely to snack is part of how the injection aids in weight loss
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