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We obtained written informed consent from all participants after a complete description of the study

Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: a possible role for lithium antioxidant effects

The review confirmed that glutathione peroxidases detoxify peroxides by a reaction coupled to GSH oxidation to GSSG with GSSG converted back to GSH by glutathione reductase and NADPH

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DOI : 10.1016/j.foodchem.2018.09.159

Contrary to the strong evidence for beneficial effects, in some studies, high doses of antioxidants such as excessive vitamin E or cysteamine have reduced motility and impaired sperm function