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Research protocols using 5-Amino-1MQ typically administer 50100mg daily via subcutaneous injection, based on human equivalent dose scaling from rodent studies where 10mg/kg bodyweight produced measurable NNMT suppression and increased NAD+ bioavailability

Weight loss typically continues beyond 48 weeks with these medications, though the rate slows considerably after the first several months

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If you experience persistent nausea or significant gastrointestinal discomfort even at 1 mg, that is also useful information