M., and Williams, G
First-line interventions include: Dietary modification : Adopting a balanced, calorie-controlled diet rich in vegetables, fruits, whole grains, and lean proteins whilst limiting processed foods, saturated fats, and added sugars Regular physical activity : Aiming for at least 150 minutes of moderate-intensity exercise weekly, which improves insulin sensitivity independent of weight loss Alcohol reduction : Even in NAFLD (non-alcohol-related), minimising alcohol consumption supports liver health Management of comorbidities : Optimising control of diabetes, hypertension, and dyslipidaemia through appropriate medications For patients with type 2 diabetes and NAFLD, medications such as pioglitazone (a thiazolidinedione) have shown benefits for liver health in addition to glycaemic control, though this is an off-label use in the UK and carries risks including fluid retention, weight gain and potential heart failure exacerbation

It's important to watch this closely and take steps to keep bones healthy and prevent breaks
Full anti-inflammatory and cardiovascular benefits also manifest during this stage
To learn more about what to expect when using Mounjaro for weight loss, talk with your doctor
3) True excess skin (significant overhang or hanging folds) If there is a meaningful amount of extra skin that cannot contract, surgery may be the only definitive option