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These larger studies will be essential in confirming the long-term efficacy and safety profile of the drug before any regulatory submission can be made

Liu H, Wang J, He T, Becker S, Zhang G, Li D, et al

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While spironolactone is generally safe when prescribed and monitored correctly, it's not without potential side effects

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The "best" choice depends on individual factors including insurance coverage, tolerability, and your physician's assessment