Effects of combination therapy on hard endpoints according to meta-analyses of observational studies In the context of real-world observational data, we have specifically analyzed 2 meta-analysis: Ahmad & Sabbour assessed 13 studies, while Colombijn et al
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Serum/plasma total Se concentrations can be influenced by sex, age, smoking, water and diet Se content, dietary sources of Se (organic or inorganic), and various conditions that increase its demands or decrease its intake/utilization, leading to decreased Se concentrations (e.g., inflammation, anorexia, intestinal malabsorption syndromes, and total enteral or parenteral nutrition without adequate Se dosing) (45, 57, 75)
(2024) 36:e14798
This degree of change cannot be explained by calorie reduction alone
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