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Appetite Effects The question about appetite is interesting because the proposed mechanism could reasonably go either direction: Reduced lipogenesis and improved metabolic flexibility could produce secondary effects on appetite regulation NAD+ restoration has complex effects on hypothalamic appetite signaling Preclinical data do not consistently describe dramatic appetite changes In human use were it to become clinically available patient-reported appetite effects would be a relevant monitoring parameter, but the data do not currently support a strong a priori expectation
Can I take Vitamin B-12 injections alongside other supplements
critical for liver health and lipid transport
Metformin, commonly prescribed for diabetes, and proton pump inhibitors used for acid reflux can both reduce B12 absorption over time
