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UK standard treatment regimens (per BNF and NHS guidance): Dietary deficiency (e.g., in vegans): oral cyanocobalamin 50150 micrograms daily between meals Pernicious anaemia or other absorption-related deficiency : intramuscular hydroxocobalamin 1 mg on alternate days for two weeks (loading), then 1 mg every two to three months as maintenance
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A physician must prescribe MOTs-C
Reported side effects in humans Clinical experience and user reports suggest that side effects, when they occur, are generally mild
Injections are appropriate only for vegans with confirmed deficiency or documented absorption problems.
B12 Deficiency and Dermatological Symptoms Patients with a vitamin B12 deficiency may notice dermatological symptoms such as hyperpigmentation, vitiligo, or dry, irritated skin
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