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Therefore, treatment with GLP-1RAs shows favorable effects on anti-inflammation through the suppression of these proinflammatory cytokine and inflammatory signal pathways, as well as augmenting cholesterol efflux in the endothelium

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When those junctions are compromised, by NSAIDs, alcohol, chronic stress, or repeated antibiotic courses, the result is a low-grade inflammatory state that shows up as bloating, systemic fatigue, food sensitivities, and immune dysregulation

Drug Discov Today 10:703710 Farngren J, Ahrn B (2019) Incretin-based medications (GLP-1 receptor agonists, DPP-4 inhibitors) as a means to avoid hypoglycaemic episodes