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TB-500 binds to actin, a structural protein inside cells, which preclinical researchers believe helps mobilize the satellite cells and fibroblasts responsible for muscle and connective-tissue regeneration

They will also set an upper limit on the total weekly dose (for example, some experts recommend not exceeding ~300 mg per week in subcutaneous dosing without further evaluation) to minimize any risk of adverse effects

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One example is splenectomy, the removal of the spleen

Any protective effect likely comes from general cellular resilience rather than direct anti-androgenic action

Royer, A