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Since 90% of the bodys serotonin originates in the gut, these peripheral effects could influence central serotonergic tone through vagal signaling

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Int Immunopharmacol 77:105969 Guo C, Huang T, Chen A, Chen X, Wang L, Shen F et al (2016) Glucagon-like peptide 1 improves insulin resistance in vitro through anti-inflammation of macrophages

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