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High-dose biotin (above 5,000 mcg) interferes with blood tests for thyroid function and troponin (cardiac markers), potentially causing misdiagnosis

Differences in expression of GSTP1 may affect the response of patients with ovarian cancer to platinum-based chemotherapy (32)

Poor sleep is associated with increased oxidative stress and reduced antioxidant capacity, including lower glutathione levels

NRF2 signaling can be activated by flavonoids and antioxidants contained in tea, vegetables, and fruit extracts

Nonetheless, further research is warranted to verify this positive clinical effect before it is approved for human consumption