Everything You Need to Know About GLP-1 Safety GLP-1 medications have become increasingly popular for managing type 2 diabetes and obesity
Only one study in 24 individuals, the majority of which were healthy, reported that DSIP can reduce the depth of anesthesia, increase heart rate and even reduce the intensity of delta-waves in these subjects [28]
Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP-1, NEJM 2021) Jastreboff AM et al
It contains tirzepatide, which acts on both GLP-1 and GIP receptors
found that in human pancreatic ductal adenocarcinoma (PDAC) cell lines, treatment with erastin induced STING1 translocation from the ER to mitochondria and triggered mitochondrial fusion by binding to MFN1/2, which led to increased mtROS levels without triggering PINK1/Parkin-independent mitophagy, eventually causing ferroptosis [117]
Others may achieve better results with tirzepatide