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In autoimmune diseases such as lupus, rheumatoid arthritis, and multiple sclerosis, chronic inflammation and oxidative stress can damage tissues and interfere with immune tolerance

That creates a vicious cycle: less GH means poorer tissue repair, more inflammation, and even worse sleep quality

It does not have anabolic or androgenic effects but aids in muscle and tissue repair (12)

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Kidney damage (rare, but possible if urine backs up into the kidneys)