Fasting glucose reductions also favored tirzepatide (approximately -68 mg/dL vs -59 mg/dL)
Further, activation of the NLRP3 cascade promotes RF through RTEC pyroptosis ( SalB enhances the nuclear accumulation of Nrf2 and suppresses NLRP3 activation, oxidative stress, and Caspase-1/Gasdermin D-mediated cellular pyroptosis via the Nrf2/NLRP3 pathway (Pang et al., 2020)
It is a chronic relapsing disease that deserves modern medical treatment
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Statistical analysis All experiments were performed independently at least three times and the data were shown as mean and S.E.M
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