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A greater percentage of patients who received RYBELSUS 14 mg once daily (8%) and RYBELSUS 7 mg once daily (4%) discontinued treatment due to gastrointestinal adverse reactions than patients who received placebo (1%)

This can happen as the medication slows digestion and food remains in the stomach for longer, increasing gas and burping

Surgery may also be considered at a BMI of 3034.9 kg/m for adults with recent-onset type 2 diabetes, and lower BMI thresholds may apply for some ethnic groups (for example, people of South Asian, Chinese, or Black African or Caribbean family background) in line with NICE guidance

Eligibility is generally based on your BMI and whether you have health conditions related to excess weight

Retatrutide is currently an unapproved, investigational compound