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Ravussin E, Lillioja S, Knowler WC, Christin L, Freymond D, Abbott WG, et al

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Periodontitis-associated salivary microbiota exacerbates colitis and anxiety in mice via gut dysbiosis and found altered metabolism of histidine in the gut and brain (Qian et al., 2023)

PMID 11934214

Niazi and Chatham list several common symptoms that occur when starting GLP-1s or with dose adjustments: Nausea or vomiting Diarrhea or constipation Heartburn or bloating Fatigue Dehydration Muscle loss Some patients may also experience hair thinning with higher doses for prolonged periods, especially when paired with low-calorie intake