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Studies indicate improvements in inflammatory markers, though again, distinguishing direct anti-inflammatory effects from those secondary to metabolic improvement remains challenging
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Moreover, medications like GnRH agonists are typically prescribed for short durations due to side effects, with fibroids often regrowing after discontinuation
The GLP-1R agonist semaglutide reshapes pancreatic cancer associated fibroblasts reducing collagen proline hydroxylation and favoring T lymphocyte infiltration
Future research should focus on elucidating the complex mechanisms underlying their psychological effects and integrating mental health considerations into therapeutic strategies
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