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skin-lightening use is not approved in many countries
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Nausea: Some individuals may experience mild nausea after receiving an injection
It also bumps up against the mechanism of action of GLP-1s, which are approved by the FDA for long-term weight management because their discontinuation can lead to weight regain
As per Bradford Hills criteria 41 , the biological plausibility through GLP-1R expression in the nervous system and temporal consistency in time-to-onset analysis support potential causality, but confounding factors inherent to spontaneous reporting systems preclude definitive conclusions
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