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The Food and Drug Administration (FDA) has approved oral formulations of Wegovy and Rybelsus

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The astute reader may have noticed that a lot of these past studies were conducted using GLP1R agonists with much shorter half-lives (GLP1 = 5 minutes, Exenatide = 2 hours, Liraglutide = 13 hours)

Not only has the Food and Drug Administration (FDA) fielded thousands of complaints tied to less expensive, compounded versions, but a 2026 Yale secret-shopper study found many online sellers of affordable GLP-1 drugs skip basic safety steps before prescribing