10.1016/j.isci.2023.106057 Summary Keywords drug mechanism, metformin, type 2 diabetes, gastrointestinal tract, gut microbiota Citation Cheng M, Ren L, Jia X, Wang J and Cong B (2024) Understanding the action mechanisms of metformin in the gastrointestinal tract
Di Domenico A, Wiedmer T, Marinoni I, Perren A
By 2035, oral formulations will expand the overall market by targeting new, hitherto unaddressed patient populations rather than taking significant share from existing injectables
The difficulty of large-scale cell sourcing further complicates clinical translation
Review describing the physiological role of GLP-1 in the central regulation of feeding behaviour, as well the effects of pharmacological stimulation of GLP-1 pathways leading to alterations in CNS activity, reduced food intake and weight loss in obesity and T2DM
It also sets up steadier energy for the day, which indirectly helps people stick to better choices later