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doi.org/10.1038/nature03000 Smart, N., et al

Ann Intern Med

Psoriatic mice treated with SFN exhibit decreased keratinocyte differentiation and reduced cutaneous inflammation Keratin 16 (K16) and keratin 17 (K17) are established markers of excessive keratinocyte hyperproliferation in psoriasis and are known to promote T-cell activation and psoriasis development [17, 18]