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Dihexa functions as a synthetic c-Met receptor agonist with oral bioavailability, amplifying endogenous HGF signaling and increasing BDNF-TrkB pathway activity by potentiating receptor-ligand binding 10,000,000-fold over natural ligands
Hooper DC, Scott GS, Zborek A, et al
Introduction The spread of antibiotic resistance in the hospital environment and in community settings particularly where biofilms are involved, has spurred development of new strategies to design innovative therapeutics to curtail the spread of resistance
CVD remains the principal cause of death and disability among patients with diabetes mellitus
Peterson, James J
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