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For therapeutic correction of deficiency , particularly in cases of pernicious anaemia or malabsorption, hydroxocobalamin injections are considered most effective in UK clinical practice

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Oral Supplements For those with dietary deficiency and normal absorption, oral B12 supplements can be effective

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You should consult a doctor if 3 , 11 : Your blood tests show elevated B12 levels without a clear cause

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As we age, mitochondrial function can decline, leading to reduced energy production and a metabolic slowdown

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Antibodies to intrinsic factor can be of two types: The blocking type, against the B12 binding site present in 70% of patients and antibodies to parietal cells present in 90% of patients, but it is less specific

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