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Instead of suppressing your appetite or forcing you to eat less, it targets the cellular machinery that tells your fat cells to store or release energy

Tamir S, Izrael S, Vaya J: The effect of oxidative stress on ERalpha and ERbeta expression

Bioresource Technology, 347 , 126579

Most importantly, this protective phenotype appears to involve the following beneficial cellular adaptions: (i) enhanced metabolism of ethanol and acetaldehyde, (ii) suppression of lipogenic genes and induction of genes involved in fatty acid oxidation, and (iii) induction of the NRF2 antioxidant response and the AMPK metabolic signaling pathway

For this group, bypassing the gut via IV or IM is often the only effective way to prevent cognitive decline

(Note that the video creator has chosen to use slightly different rules