The first 48 weeks are typically when side effects peak , nausea, constipation, low energy, and the steepest drop in appetite as your dose escalates
This is one of the key drivers of mitochondrial failure, accumulation of irreparable DNA damage and cellular aging across tissues
Its also important to remember that its not meant to be a solution on its own For best results, and especially to maintain them long-term, youll need to make healthy lifestyle choices alongside the treatment
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We also know that weight loss reverses the natural progression of AF and is associated with improved outcomes in obese patients
Moderate age-related decline necessitates more stimulation than younger patients but most retain adequate pituitary reserve for good response